XPH Holdings — State Street(R) SPDR(R) S&P(R) Pharmaceuticals ETF
Data updated: 2026-09-11
XPH holds 67 securities. The top 10 make up 28.9% of net assets, led by State Street Navigator Securities Lending Portfolio II (8.58%) and Definium Therapeutics (3.09%). Health Care (92.0%) and Funds & ETFs (8.0%) are the largest sectors, and 98.4% of the portfolio is in United States. No debt holdings are reported.
Holdings cover 108.59% of net asset value (99.99% of total assets; remainder is cash and receivables). As of June 30, 2026 · N-PORT.
XPH Portfolio Holdings
67 holdings of State Street(R) SPDR(R) S&P(R) Pharmaceuticals ETF by percentage of net assets, from the fund's SEC N-PORT filing as of June 30, 2026.
| Holding | Ticker | Sector | % of net assets | Value (USD) |
|---|---|---|---|---|
| State Street Navigator Securities Lending Portfolio II | — | Funds & ETFs | 8.58% | $36.75M |
| Definium Therapeutics Inc | DFTX | Health Care | 3.09% | $13.23M |
| MBX Biosciences Inc | MBX | Health Care | 2.72% | $11.65M |
| Alumis Inc | ALMS | Health Care | 2.14% | $9.17M |
| AtaiBeckley Inc | ATAI | Health Care | 2.13% | $9.11M |
| Trevi Therapeutics Inc | TRVI | Health Care | 2.12% | $9.10M |
| Enliven Therapeutics Inc | ELVN | Health Care | 2.09% | $8.97M |
| Amylyx Pharmaceuticals Inc | AMLX | Health Care | 2.04% | $8.72M |
| VeraDermics Inc | MANE | Health Care | 2.02% | $8.64M |
| Ligand Pharmaceuticals Inc | LGND | Health Care | 1.94% | $8.32M |
| Nuvation Bio Inc | NUVB | Health Care | 1.89% | $8.11M |
| Edgewise Therapeutics Inc | EWTX | Health Care | 1.88% | $8.07M |
| Nektar Therapeutics | NKTR | Health Care | 1.88% | $8.04M |
| Liquidia Corp | LQDA | Health Care | 1.86% | $7.99M |
| Maze Therapeutics Inc | MAZE | Health Care | 1.85% | $7.93M |
| Harrow Inc | HROW | Health Care | 1.81% | $7.73M |
| EyePoint Inc | EYPT | Health Care | 1.77% | $7.58M |
| Amneal Pharmaceuticals Inc | AMRX | Health Care | 1.72% | $7.39M |
| Ocular Therapeutix Inc | OCUL | Health Care | 1.71% | $7.35M |
| Corcept Therapeutics Inc | CORT | Health Care | 1.70% | $7.28M |
| Crinetics Pharmaceuticals Inc | CRNX | Health Care | 1.66% | $7.13M |
| Pacira BioSciences Inc | PCRX | Health Care | 1.65% | $7.08M |
| Merck & Co Inc | MRK | Health Care | 1.65% | $7.05M |
| Indivior Pharmaceuticals Inc | INDV | Health Care | 1.64% | $7.04M |
| Elanco Animal Health Inc | ELAN | Health Care | 1.64% | $7.04M |
| Johnson & Johnson | JNJ | Health Care | 1.63% | $6.96M |
| Eli Lilly & Co | LLY | Health Care | 1.61% | $6.91M |
| Jazz Pharmaceuticals PLC | JAZZ | Health Care | 1.60% | $6.86M |
| Collegium Pharmaceutical Inc | COLL | Health Care | 1.59% | $6.80M |
| Bristol-Myers Squibb Co | BMY | Health Care | 1.58% | $6.78M |
| Supernus Pharmaceuticals Inc | SUPN | Health Care | 1.57% | $6.74M |
| Royalty Pharma PLC | RPRX | Health Care | 1.57% | $6.72M |
| Tarsus Pharmaceuticals Inc | TARS | Health Care | 1.57% | $6.72M |
| WaVe Life Sciences Ltd | — | Health Care | 1.57% | $6.71M |
| Harmony Biosciences Holdings Inc | HRMY | Health Care | 1.57% | $6.71M |
| Organon & Co | OGN | Health Care | 1.54% | $6.62M |
| ANI Pharmaceuticals Inc | ANIP | Health Care | 1.54% | $6.61M |
| Viatris Inc | VTRS | Health Care | 1.54% | $6.58M |
| Esperion Therapeutics Inc | ESPR | Health Care | 1.54% | $6.58M |
| Axsome Therapeutics Inc | AXSM | Health Care | 1.52% | $6.50M |
| Innoviva Inc | INVA | Health Care | 1.51% | $6.46M |
| BioAge Labs Inc | BIOA | Health Care | 1.50% | $6.43M |
| Prestige Consumer Healthcare Inc | PBH | Health Care | 1.47% | $6.29M |
| Rapport Therapeutics Inc | RAPP | Health Care | 1.44% | $6.16M |
| Pfizer Inc | PFE | Health Care | 1.44% | $6.15M |
| Omeros Corp | OMER | Health Care | 1.42% | $6.10M |
| Perrigo Co PLC | PRGO | Health Care | 1.42% | $6.08M |
| Xeris Biopharma Holdings Inc | XERS | Health Care | 1.39% | $5.97M |
| Zoetis Inc | ZTS | Health Care | 1.35% | $5.78M |
| Eton Pharmaceuticals Inc | ETON | Health Care | 1.30% | $5.59M |
| Phibro Animal Health Corp | PAHC | Health Care | 1.28% | $5.50M |
| Amphastar Pharmaceuticals Inc | AMPH | Health Care | 1.25% | $5.36M |
| Arvinas Inc | ARVN | Health Care | 1.25% | $5.34M |
| Zevra Therapeutics Inc | ZVRA | Health Care | 1.24% | $5.30M |
| Alto Neuroscience Inc | ANRO | Health Care | 1.17% | $5.02M |
| Phathom Pharmaceuticals Inc | PHAT | Health Care | 1.06% | $4.55M |
| Relmada Therapeutics Inc | RLMD | Health Care | 1.06% | $4.53M |
| CorMedix Inc | CRMD | Health Care | 1.01% | $4.32M |
| Septerna Inc | SEPN | Health Care | 0.99% | $4.24M |
| Theravance Biopharma Inc | — | Health Care | 0.96% | $4.10M |
| Aclaris Therapeutics Inc | ACRS | Health Care | 0.89% | $3.83M |
| LB Pharmaceuticals Inc | LBRX | Health Care | 0.80% | $3.41M |
| Aquestive Therapeutics Inc | AQST | Health Care | 0.76% | $3.28M |
| Fulcrum Therapeutics Inc | FULC | Health Care | 0.69% | $2.96M |
| Lexicon Pharmaceuticals Inc | LXRX | Health Care | 0.63% | $2.69M |
| Evolus Inc | EOLS | Health Care | 0.53% | $2.26M |
| State Street Institutional US Government Money Market Fund | — | Funds & ETFs | 0.06% | $265.61K |
XPH Sector Allocation
State Street(R) SPDR(R) S&P(R) Pharmaceuticals ETF holdings grouped by sector, by share of the portfolio's market value.
| Sector | Weight | Holdings |
|---|---|---|
| Health Care | 92.0% | 65 |
| Funds & ETFs | 8.0% | 2 |
XPH Country Allocation
Where State Street(R) SPDR(R) S&P(R) Pharmaceuticals ETF's holdings are domiciled, by percentage of net assets (largest 6).
| Country | % of net assets |
|---|---|
| United States | 98.4% |
| Canada | 3.1% |
| Ireland | 3.0% |
| United Kingdom | 1.6% |
| Singapore | 1.6% |
| Cayman Islands | 1.0% |
XPH Portfolio Allocation
Asset-class allocation of State Street(R) SPDR(R) S&P(R) Pharmaceuticals ETF by percentage of net assets, from the latest SEC N-PORT filing.
| Asset class | Allocation |
|---|---|
| Equity | 99.9% |
| Cash & Equivalents | 8.6% |
For information only. Not investment advice: figures are as reported in SEC filings and may contain errors or be out of date. Past performance does not guarantee future results.