XBI Performance — State Street(R) SPDR(R) S&P(R) Biotech ETF

Data updated: 2026-09-11

XBI returned +29.82% year to date and +91.71% over one year to Jun 2026. Annualised returns are +24.11% over 3 years and +3.26% over 5 years. The fund beat its Health Care Equity category average: $100 invested three years ago grew to $191, against $138 for the category, and to $192 over one year, against $137. Volatility over the past three years was 25.54% a year. In the 12 months to Jun 2026 the fund took in a net $1.3B, and assets reached $10.73B.

XBI Growth of $100

What $100 invested in State Street(R) SPDR(R) S&P(R) Biotech ETF grew to, compounded from monthly returns reported on SEC Form N-PORT, against the Health Care Equity category average over the same months.

PeriodXBICategory average
1 year (Jul 2025 – Jun 2026)$192$137
3 years (Jul 2023 – Jun 2026)$191$138
5 years (Jul 2021 – Jun 2026)$117$121
Since data start (Jul 2019 – Jun 2026)$182$182

XBI Trailing Returns

Total returns to Jun 2026, from SEC N-PORT.

PeriodTotal return
YTD+29.82%
1 year+91.71%
3 years (annualised)+24.11%
5 years (annualised)+3.26%

XBI Annual Returns

Calendar-year total returns of State Street(R) SPDR(R) S&P(R) Biotech ETF, compounded from monthly SEC N-PORT returns. Partial years show the months covered.

YearTotal return
2026 (Jan–Jun)+29.82%
2025+35.84%
2024+1.09%
2023+7.48%
2022−25.76%
2021−20.53%
2020+48.20%
2019 (Jul–Dec)+8.44%

XBI Monthly Returns

Monthly total returns as reported on SEC Form N-PORT.

YearJanFebMarAprMayJunJulAugSepOctNovDec
2026+2.3%+2.1%+0.2%+2.8%+4.1%+15.8%——————
2025+2.8%−4.2%−8.6%+2.4%−4.6%+4.7%+3.3%+4.9%+11.5%+12.6%+9.2%−0.6%
2024−1.9%+12.4%−3.4%−11.1%+5.3%+4.3%+6.8%+2.3%−2.4%−1.9%+2.6%−9.5%
2023+7.2%−6.9%−8.1%+5.3%+4.9%−1.1%+1.2%−6.1%−7.7%−9.3%+14.0%+18.3%
2022−16.3%−4.0%0.0%−18.0%−6.8%+7.9%+9.2%+3.3%−5.2%+3.5%+2.0%−0.8%
2021+8.5%−3.2%−8.2%+0.8%−6.4%+6.0%−8.9%+7.7%−5.4%−0.8%−6.8%−3.8%
2020−6.5%+0.2%−13.1%+20.4%+10.9%+8.1%−2.6%+2.4%−0.2%+1.0%+18.3%+5.9%
2019——————−2.4%−6.2%−5.1%+7.0%+14.7%+1.8%

XBI Risk

Risk measures from monthly returns over Jul 2023 – Jun 2026.

  • 3-year volatility (annualised): 25.54%
  • 3-year Sharpe ratio: 0.77 (vs 4.5% risk-free rate)
  • Best month: +18.27% (Dec 2023)
  • Worst month: −11.07% (Apr 2024)

XBI Fund Flows

Monthly money in and out of State Street(R) SPDR(R) S&P(R) Biotech ETF, from SEC Form N-PORT.

  • 12-month net flow: $1.3B
  • 12-month gross sales (incl. reinvestments): $30.8B
  • Sales ÷ redemptions: 1.05×
MonthSalesRedemptionsNet flow
Jun 2026$3.5B$2.6B$918.7M
May 2026$2.2B$2.4B−$223.6M
Apr 2026$3.3B$2.7B$633.3M
Mar 2026$2.9B$3.5B−$589.5M
Feb 2026$2.7B$3.1B−$443.2M
Jan 2026$2.6B$2.3B$307.4M
Dec 2025$2.4B$2.8B−$390.1M
Nov 2025$3.7B$2.9B$779.4M
Oct 2025$3.0B$2.5B$427.7M
Sep 2025$1.5B$1.4B$96.0M
Aug 2025$1.7B$1.7B$15.4M
Jul 2025$1.3B$1.5B−$200.2M

XBI Assets Under Management

Net assets of State Street(R) SPDR(R) S&P(R) Biotech ETF by report date, from SEC N-PORT filings.

Report dateNet assets
2026-06-30$10.73B
2026-03-31$7.43B
2025-12-31$7.85B
2025-09-30$5.71B
2025-06-30$4.83B
2025-03-31$5.12B
2024-12-31$6.37B
2024-09-30$7.70B
2024-06-30$7.13B
2024-03-31$7.55B
2023-12-31$6.99B
2023-09-30$5.50B

For information only. Not investment advice: figures are as reported in SEC filings and may contain errors or be out of date. Past performance does not guarantee future results.