SHSAX Holdings — BlackRock Health Sciences Opportunities Portfolio
Data updated: 2026-09-25
SHSAX holds 155 securities. The top 10 make up 52.0% of net assets, led by Eli Lilly & Company.com (12.29%) and Johnson & Johnson.com (8.77%). Health Care (98.6%) and Funds & ETFs (1.4%) are the largest sectors, and 93.9% of the portfolio is in United States. Debt holdings: 1 position, under 0.1% of assets.
Holdings cover 101.14% of net asset value (99.77% of total assets; remainder is cash and receivables). As of May 29, 2026 · N-PORT.
SHSAX Portfolio Holdings
155 holdings of BlackRock Health Sciences Opportunities Portfolio by percentage of net assets, from the fund's SEC N-PORT filing as of May 29, 2026. The 100 largest are listed below; the interactive table on this page lists all 155.
| Holding | Ticker | Sector | % of net assets | Value (USD) |
|---|---|---|---|---|
| Eli Lilly & Company.com | LLY | Health Care | 12.29% | $725.60M |
| Johnson & Johnson.com | JNJ | Health Care | 8.77% | $518.08M |
| Unitedhealth Group Inc.com | UNH | Health Care | 6.10% | $360.31M |
| Merck & Company Inc.com | MRK | Health Care | 4.94% | $291.63M |
| Gilead Sciences Inc.com | GILD | Health Care | 4.19% | $247.53M |
| Abbvie Inc.com | ABBV | Health Care | 3.94% | $232.53M |
| Amgen Inc.com | AMGN | Health Care | 3.37% | $198.77M |
| Thermo Fisher Scientific Inc.com | TMO | Health Care | 3.02% | $178.45M |
| Vertex Pharmaceuticals Inc.com | VRTX | Health Care | 2.74% | $161.97M |
| Pfizer Inc.com | PFE | Health Care | 2.61% | $154.44M |
| Edwards Lifesciences Corp.com | EW | Health Care | 2.51% | $147.95M |
| Danaher Corp.com | DHR | Health Care | 2.00% | $117.85M |
| Abbott Laboratories.com | ABT | Health Care | 1.97% | $116.58M |
| Intuitive Surgical Inc.com New | ISRG | Health Care | 1.95% | $115.26M |
| Teva Pharmaceutical Industries Ltd. Sponsored ADS | TEVA | Health Care | 1.87% | $110.25M |
| Boston Scientific Corp.com | BSX | Health Care | 1.59% | $93.96M |
| Elevance Health Inc.com | ELV | Health Care | 1.56% | $92.38M |
| Argenx SE Sponsored ADR | ARGX | Health Care | 1.26% | $74.40M |
| Biogen Inc.com | BIIB | Health Care | 1.21% | $71.38M |
| Astrazeneca PLC Ord Usd0.25 | AZN | Health Care | 1.21% | $71.36M |
| Stryker Corp.com | SYK | Health Care | 1.15% | $67.71M |
| Blackrock Funds Iii Instl Mmkt | BISXX | Funds & ETFs | 1.01% | $59.51M |
| Revolution Medicines Inc.com | RVMD | Health Care | 0.96% | $56.90M |
| Humana Inc.com | HUM | Health Care | 0.92% | $54.43M |
| Regeneron Pharmaceuticals Inc.com | REGN | Health Care | 0.91% | $53.89M |
| Bristol-Myers Squibb Company.com | BMY | Health Care | 0.89% | $52.44M |
| Cogent Biosciences Inc.com | COGT | Health Care | 0.83% | $49.18M |
| Dexcom Inc.com | DXCM | Health Care | 0.83% | $48.95M |
| Waters Corp.com | WAT | Health Care | 0.81% | $47.73M |
| Cytokinetics Inc.com New | CYTK | Health Care | 0.75% | $44.15M |
| Penumbra Inc.com | PEN | Health Care | 0.72% | $42.40M |
| Hca Healthcare Inc.com | HCA | Health Care | 0.72% | $42.26M |
| Insmed Inc.com Par $.01 | INSM | Health Care | 0.71% | $41.92M |
| Cvs Health Corp.com | CVS | Health Care | 0.71% | $41.82M |
| Rhythm Pharmaceuticals Inc.com | RYTM | Health Care | 0.70% | $41.62M |
| Galderma Group AG Chf0.01 | GALD | Health Care | 0.67% | $39.79M |
| Incyte Corp.com | INCY | Health Care | 0.65% | $38.33M |
| Novartis AG Sponsored ADR | NVS | Health Care | 0.64% | $37.79M |
| Protagonist Therapeutics Inc.com | PTGX | Health Care | 0.62% | $36.88M |
| Agilent Technologies Inc.com | A | Health Care | 0.62% | $36.76M |
| Idexx Laboratories Inc.com | IDXX | Health Care | 0.62% | $36.69M |
| Nuvalent Inc.com | NUVL | Health Care | 0.59% | $34.87M |
| United Therapeutics Corp.com | UTHR | Health Care | 0.53% | $31.01M |
| Alnylam Pharmaceuticals Inc.com | ALNY | Health Care | 0.49% | $28.66M |
| Bruker Corp.com | BRKR | Health Care | 0.47% | $27.79M |
| Moderna Inc.com | MRNA | Health Care | 0.45% | $26.46M |
| Iqvia Holdings Inc.com | IQV | Health Care | 0.44% | $25.73M |
| Illumina Inc.com | ILMN | Health Care | 0.40% | $23.78M |
| Medline Inc.com Cl A | MDLN | Health Care | 0.37% | $22.12M |
| Apogee Therapeutics Inc.com | APGE | Health Care | 0.37% | $21.66M |
| Blackrock Liquidity Funds T Fund Instl Shs | TSTXX | Funds & ETFs | 0.36% | $21.27M |
| Mckesson Corp.com | MCK | Health Care | 0.35% | $20.48M |
| Biomarin Pharmaceutical Inc.com | BMRN | Health Care | 0.31% | $18.48M |
| Neurocrine Biosciences Inc.com | NBIX | Health Care | 0.30% | $17.89M |
| Dianthus Therapeutics Inc.com | DNTH | Health Care | 0.29% | $17.34M |
| Roivant Sciences Ltd. Shs | ROIV | Health Care | 0.29% | $16.91M |
| Quest Diagnostics Inc.com | DGX | Health Care | 0.28% | $16.60M |
| Lb Pharmaceuticals Inc.com Shs | LBRX | Health Care | 0.27% | $15.88M |
| Ucb SA Npv | UCB | Health Care | 0.27% | $15.73M |
| Oruka Therapeutics Inc.com | ORKA | Health Care | 0.26% | $15.50M |
| Stoke Therapeutics Inc.com | STOK | Health Care | 0.25% | $14.63M |
| Arcus Biosciences Inc.com | RCUS | Health Care | 0.25% | $14.51M |
| Madrigal Pharmaceuticals Inc.com | MDGL | Health Care | 0.23% | $13.72M |
| Ionis Pharmaceuticals Inc.com | IONS | Health Care | 0.22% | $13.01M |
| Cencora Inc.com | COR | Health Care | 0.21% | $12.47M |
| Exelixis Inc.com | EXEL | Health Care | 0.20% | $11.69M |
| Elanco Animal Health Inc.com | ELAN | Health Care | 0.20% | $11.53M |
| Daiichi Sankyo Company Ltd. Npv | 4568 | Health Care | 0.19% | $11.34M |
| Scholar Rock Holding Corp.com | SRRK | Health Care | 0.19% | $11.15M |
| Adarx Pharmaceuticals, Inc. | — | Health Care | 0.18% | $10.89M |
| Kailera Therapeutics, Inc. Common Stock | KLRA | Health Care | 0.18% | $10.65M |
| West Pharmaceutical Services Inc.com | WST | Health Care | 0.18% | $10.50M |
| Mbx Biosciences Inc.com | MBX | Health Care | 0.18% | $10.49M |
| Natera Inc.com | NTRA | Health Care | 0.17% | $10.32M |
| Charles River Laboratories International Inc.com | CRL | Health Care | 0.17% | $10.15M |
| Bio-Techne Corp.com | TECH | Health Care | 0.17% | $10.02M |
| Kailera Therapeutics, Inc. | — | Health Care | 0.17% | $9.82M |
| Novocure Ltd.com Usd0.00 | NVCR | Health Care | 0.17% | $9.79M |
| Intellia Therapeutics Inc.com | NTLA | Health Care | 0.16% | $9.35M |
| Erasca Inc.com | ERAS | Health Care | 0.15% | $9.11M |
| Viridian Therapeutics Inc.com | VRDN | Health Care | 0.15% | $9.09M |
| Glaukos Corp.com | GKOS | Health Care | 0.15% | $9.01M |
| Axsome Therapeutics Inc.com | AXSM | Health Care | 0.15% | $8.95M |
| Bright Minds Biosciences Inc.com New | DRUG | Health Care | 0.14% | $8.42M |
| Agios Pharmaceuticals Inc.com | AGIO | Health Care | 0.14% | $7.99M |
| Eikon Therapeutics Inc.com | EIKN | Health Care | 0.13% | $7.83M |
| Vaxcyte Inc.com | PCVX | Health Care | 0.13% | $7.57M |
| Laronde, Inc. | — | Health Care | 0.13% | $7.47M |
| Mettler-Toledo International Inc.com | MTD | Health Care | 0.12% | $7.15M |
| Kartos Therapeutics, Inc. | — | Health Care | 0.12% | $6.98M |
| Angitia Biopharmaceuticals Limited | — | Health Care | 0.11% | $6.52M |
| Enanta Pharmaceuticals Inc.com | ENTA | Health Care | 0.11% | $6.47M |
| Alumis Inc.com | ALMS | Health Care | 0.11% | $6.34M |
| Immunome Inc.com | IMNM | Health Care | 0.11% | $6.30M |
| Monte Rosa Therapeutics Inc.com | GLUE | Health Care | 0.11% | $6.27M |
| Genesis Therapeutics, Inc. | — | Health Care | 0.10% | $6.09M |
| Bridgebio Oncology Therapeutics Inc.com New | BBOT | Health Care | 0.10% | $6.04M |
| Palvella Therapeutics Inc.com | PVLA | Health Care | 0.10% | $6.01M |
| Radnet Inc.com | RDNT | Health Care | 0.10% | $6.00M |
| Bridgebio Pharma Inc.com | BBIO | Health Care | 0.10% | $5.76M |
SHSAX Sector Allocation
BlackRock Health Sciences Opportunities Portfolio holdings grouped by sector, by share of the portfolio's market value.
| Sector | Weight | Holdings |
|---|---|---|
| Health Care | 98.6% | 151 |
| Funds & ETFs | 1.4% | 2 |
| Financials | 0.0% | 1 |
| Unknown | 0.0% | 1 |
SHSAX Country Allocation
Where BlackRock Health Sciences Opportunities Portfolio's holdings are domiciled, by percentage of net assets (largest 15).
| Country | % of net assets |
|---|---|
| United States | 93.9% |
| Israel | 1.9% |
| Switzerland | 1.4% |
| United Kingdom | 1.4% |
| Netherlands | 1.3% |
| Bermuda | 0.3% |
| Belgium | 0.3% |
| Japan | 0.2% |
| Canada | 0.2% |
| Jersey | 0.2% |
| British Virgin Islands | 0.1% |
| Germany | 0.1% |
| Denmark | 0.1% |
| Cayman Islands | 0.1% |
| Singapore | 0.0% |
SHSAX Portfolio Allocation
Asset-class allocation of BlackRock Health Sciences Opportunities Portfolio by percentage of net assets, from the latest SEC N-PORT filing.
| Asset class | Allocation |
|---|---|
| Equity | 99.8% |
| Cash & Equivalents | 1.4% |
For information only. Not investment advice: figures are as reported in SEC filings and may contain errors or be out of date. Past performance does not guarantee future results.