SHISX — BlackRock Health Sciences Opportunities Portfolio
Data updated: 2026-07-27
SHISX — BlackRock Health Sciences Opportunities Portfolio data: holdings, portfolio allocation, expenses, performance, cashflows, risk and SEC filings. United States Health Care Equity · $5.91B AUM · 1.15% expense ratio · 10.5% 1-yr return. From SEC regulatory filings.
SHISX Fund Overview
SHISX — BlackRock Health Sciences Opportunities Portfolio is a US mutual fund managed by Blackrock Funds, categorised as United States Health Care Equity. ABC INVEST provides holdings, performance, costs, cashflows, risk data, prospectus documents and SEC filings, sourced from SEC filings.
- Type: US mutual fund
- Manager: Blackrock Funds
- Category: United States Health Care Equity
- Assets under management: $5.91B
- 1-year return: 10.5%
- Ticker: SHISX
- SEC CIK: 0000844779
- SEC series ID: S000001877
- Share class ID: C000004913
SHISX Holdings
Top 10 holdings of BlackRock Health Sciences Opportunities Portfolio by percentage of net assets, from the fund's latest SEC N-PORT filing.
| Holding | % of net assets |
|---|---|
| Eli Lilly & Company | 12.29% |
| Johnson & Johnson | 8.77% |
| Unitedhealth Group, Inc. | 6.10% |
| Merck & Company, Inc. | 4.94% |
| Gilead Sciences, Inc. | 4.19% |
| Abbvie, Inc. | 3.94% |
| Amgen, Inc. | 3.37% |
| Thermo Fisher Scientific, Inc. | 3.02% |
| Vertex Pharmaceuticals, Inc. | 2.74% |
| Pfizer, Inc. | 2.61% |
SHISX Portfolio Allocation
Asset-class allocation of BlackRock Health Sciences Opportunities Portfolio by percentage of net assets, from the latest SEC N-PORT filing.
| Asset class | Allocation |
|---|---|
| Equity | 99.8% |
| Cash & Equivalents | 1.4% |
SHISX Performance
Total returns for SHISX (as of 2026-08-01), from SEC filings.
| Period | Total return |
|---|---|
| YTD | 2.4% |
| 1 year | 10.5% |
| 3 years (annualised) | 10.4% |
| 5 years (annualised) | 6.4% |
SHISX Risk Information
Risk metrics for SHISX, derived from monthly returns in SEC filings.
- 1-year volatility (annualised): 13.8%
SHISX Costs and Fees
SHISX costs about $115 per $10,000 invested per year in fund expenses.
- Net expense ratio: 1.15%
- Gross expense ratio: 1.15%
- Portfolio turnover: 43%
- Brokerage commissions: 1.83 bps of average net assets (SEC N-CEN)
SHISX Cashflows
Over the 12 months to 2026-02, BlackRock Health Sciences Opportunities Portfolio had net outflows of $845.47M, from monthly SEC N-PORT filings.
| Month | Net flow |
|---|---|
| 2026-02 | −$81.94M |
| 2026-01 | −$76.61M |
| 2025-12 | $172.30M |
| 2025-11 | −$83.09M |
| 2025-10 | −$127.81M |
| 2025-09 | −$172.11M |
SHISX Debt Constituents
No individual debt constituents are reported in BlackRock Health Sciences Opportunities Portfolio's latest SEC N-PORT filing.
SHISX Prospectus and SEC Filings
Official BlackRock Health Sciences Opportunities Portfolio filings on SEC EDGAR — prospectus, portfolio holdings and annual reports.
Related Funds
Other United States Health Care Equity funds tracked on ABC INVEST:
Data Sources
ABC INVEST compiles this page from public filings made to the U.S. Securities and Exchange Commission (SEC) through EDGAR: portfolio holdings and monthly cashflows from Form N-PORT, expenses and returns from fund prospectuses (Form 485BPOS) and the SEC DERA Risk/Return Summary data sets, annual data from Form N-CEN, and shareholder reports from Form N-CSR.