JFNCX Performance — Janus Henderson Global Life Sciences Fund, Class C

Data updated: 2026-08-26

JFNCX returned +8.11% year to date and +38.20% over one year to Jun 2026. Annualised returns are +12.42% over 3 years and +7.54% over 5 years. The fund beat its Global Health Care Equity category average: $100 invested three years ago grew to $142, against $130 for the category, and to $138 over one year, against $124. Volatility over the past three years was 15.69% a year. In the 12 months to Jun 2026 the fund lost a net $20.5M, and assets reached $5.81B.

JFNCX Growth of $100

What $100 invested in Janus Henderson Global Life Sciences Fund grew to, compounded from monthly returns reported on SEC Form N-PORT, against the Global Health Care Equity category average over the same months.

PeriodJFNCXCategory average
1 year (Jul 2025 – Jun 2026)$138$124
3 years (Jul 2023 – Jun 2026)$142$130
5 years (Jul 2021 – Jun 2026)$144$104
Since data start (Jul 2019 – Jun 2026)$220$160

JFNCX Trailing Returns

Total returns to Jun 2026, from SEC N-PORT.

PeriodTotal return
YTD+8.11%
1 year+38.20%
3 years (annualised)+12.42%
5 years (annualised)+7.54%

JFNCX Annual Returns

Calendar-year total returns of Janus Henderson Global Life Sciences Fund, compounded from monthly SEC N-PORT returns. Partial years show the months covered.

YearTotal return
2026 (Jan–Jun)+8.11%
2025+23.68%
2024+2.65%
2023+6.48%
2022−3.53%
2021+5.88%
2020+24.45%
2019 (Jul–Dec)+18.50%

JFNCX Monthly Returns

Monthly total returns as reported on SEC Form N-PORT.

YearJanFebMarAprMayJunJulAugSepOctNovDec
2026+0.7%+2.0%−6.5%+1.8%+2.3%+8.1%——————
2025+5.9%−0.3%−4.5%−0.4%−5.8%+2.3%−0.9%+6.0%+2.8%+8.6%+9.2%−0.2%
2024+1.7%+3.8%+2.7%−4.7%+3.5%+3.1%+2.6%+5.1%−2.5%−3.4%−0.8%−7.6%
2023+2.6%−4.4%+0.4%+2.9%−2.4%+4.0%−3.8%−1.5%+0.9%+7.5%+7.3%−6.2%
2022+3.5%+0.5%−9.1%−0.8%−1.0%−6.8%−3.0%−2.6%+3.6%−0.9%+5.9%+8.5%
2021−2.0%0.0%−0.9%+3.5%+0.2%+3.0%−4.2%+3.1%+0.1%+6.7%−7.4%+4.4%
2020−6.0%−5.6%−2.9%+2.1%+5.1%+12.5%−0.8%+3.6%+2.1%+4.9%+10.9%−2.1%
2019——————0.0%0.0%0.0%+4.0%+8.3%+5.2%

JFNCX Risk

Risk measures from monthly returns over Jul 2023 – Jun 2026.

  • 3-year volatility (annualised): 15.69%
  • 3-year Sharpe ratio: 0.50 (vs 4.5% risk-free rate)
  • Best month: +9.21% (Nov 2025)
  • Worst month: −7.58% (Dec 2024)

JFNCX Fund Flows

Monthly money in and out of Janus Henderson Global Life Sciences Fund, from SEC Form N-PORT.

  • 12-month net flow: −$20.5M
  • 12-month gross sales (incl. reinvestments): $1.0B
  • Sales ÷ redemptions: 0.98×
MonthSalesRedemptionsNet flow
Jun 2026$58.5M$85.1M−$26.6M
May 2026$63.8M$75.7M−$11.9M
Apr 2026$71.3M$83.5M−$12.2M
Mar 2026$87.3M$74.8M$12.5M
Feb 2026$100.9M$67.6M$33.3M
Jan 2026$81.3M$87.7M−$6.4M
Dec 2025$316.4M$107.9M$208.5M
Nov 2025$63.4M$78.4M−$15.1M
Oct 2025$58.2M$79.0M−$20.8M
Sep 2025$41.6M$82.3M−$40.7M
Aug 2025$51.5M$112.5M−$60.9M
Jul 2025$39.3M$119.4M−$80.1M

JFNCX Assets Under Management

Net assets of Janus Henderson Global Life Sciences Fund by report date, from SEC N-PORT filings.

Report dateNet assets
2026-06-30$5.81B
2026-03-31$5.20B
2025-12-31$5.36B
2025-09-30$4.57B
2025-06-30$4.40B
2025-03-31$4.71B
2024-12-31$4.78B
2024-09-30$5.73B
2024-06-30$5.47B
2024-03-31$5.37B
2023-12-31$4.90B
2023-09-30$4.58B

For information only. Not investment advice: figures are as reported in SEC filings and may contain errors or be out of date. Past performance does not guarantee future results.